MicroRNA-208a Dysregulates Apoptosis Genes Expression and Promotes Cardiomyocyte Apoptosis during Ischemia and Its Silencing Improves Cardiac Function after Myocardial Infarction

Aims. miR-208a is associated with adverse outcomes in several cardiac pathologies known to have increased apoptosis, including myocardial infarction (MI). We investigated if miR-208a has proapoptotic effects on ischemic cardiomyocytes and if its silencing has therapeutic benefits in MI. Methods and...

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Bibliografiske detaljer
Udgivet i:Mediators Inflamm
Main Authors: Tony, Hasahya, Meng, Kai, Wu, Bangwei, Yu, Aijia, Zeng, Qiutang, Yu, Kunwu, Zhong, Yucheng
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673358/
https://ncbi.nlm.nih.gov/pubmed/26688617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/479123
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