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Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies

Optimal animal models of muscle invasive bladder cancer (MIBC) are necessary to overcome the current lack of novel targeted therapies for this malignancy. Here we report on the establishment and characterization of patient-derived primary xenografts (PDX). Patient tumors were grafted under the renal...

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Pubblicato in:Oncotarget
Autori principali: Jäger, Wolfgang, Xue, Hui, Hayashi, Tetsutaro, Janssen, Claudia, Awrey, Shannon, Wyatt, Alexander W., Anderson, Shawn, Moskalev, Igor, Haegert, Anne, Alshalalfa, Mohammed, Erho, Nicholas, Davicioni, Elai, Fazli, Ladan, Li, Estelle, Collins, Colin, Wang, Yuzhuo, Black, Peter C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673283/
https://ncbi.nlm.nih.gov/pubmed/26041878
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