TMEM196 acts as a novel functional tumour suppressor inactivated by DNA methylation and is a potential prognostic biomarker in lung cancer

Epigenetic silencing of tumour suppressors contributes to the development and progression of lung cancer. We recently found that TMEM196 was hypermethylated in lung cancer. This study aimed to clarify its epigenetic regulation, possible roles and clinical significance. TMEM196 methylation correlated...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Liu, Wen-bin, Han, Fei, Jiang, Xiao, Chen, Hong-qiang, Zhao, Huan, Liu, Yong, Li, Yong-hong, Huang, Chuanshu, Cao, Jia, Liu, Jin-yi
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673261/
https://ncbi.nlm.nih.gov/pubmed/26056045
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