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The TRAF-interacting protein (TRAIP) is a novel E2F target with peak expression in mitosis

The TRAF-interacting protein (TRAIP) is an E3 ubiquitin ligase required for cell proliferation. TRAIP mRNA is downregulated in human keratinocytes after inhibition of the PI3K/AKT/mTOR signaling. Since E2F transcription factors are downstream of PI3K/AKT/mTOR we investigated whether they regulate TR...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chapard, Christophe, Hohl, Daniel, Huber, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673240/
https://ncbi.nlm.nih.gov/pubmed/26369285
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