Combination genetic signature stratifies lower-grade gliomas better than histological grade

We studied if combination genetic signature potentially stratifies lower-grade gliomas better than histology by investigating 214 lower-grade gliomas for IDH1/2 and TERTp mutations, 1p/19q codeletion and EGFR amplification as to their impact on prognostication. Prognostic association of grading was...

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Pubblicato in:Oncotarget
Autori principali: Chan, Aden Ka-Yin, Yao, Yu, Zhang, Zhenyu, Shi, Zhifeng, Chen, Liang, Chung, Nellie Yuk-Fei, Liu, Joseph Shu-Ming, Li, Kay Ka-Wai, Chan, Danny Tat-Ming, Poon, Wai Sang, Wang, Ying, Zhou, Liangfu, Ng, Ho-Keung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper: Pathology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673237/
https://ncbi.nlm.nih.gov/pubmed/26369702
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