In vivo selection for spine-derived highly metastatic lung cancer cells is associated with increased migration, inflammation and decreased adhesion

We developed a murine spine metastasis model by screening five metastatic non-small cell lung cancer cell lines (PC-9, A549, NCI-H1299, NCI-H460, H2030). A549 cells displayed the highest tendency towards spine metastases. After three rounds of selection in vivo, we isolated a clone named A549L6, whi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cai, Xiaopan, Luo, Jian, Yang, Xinghai, Deng, Huayun, Zhang, Jishen, Li, Shichang, Wei, Haifeng, Yang, Cheng, Xu, Leqin, Jin, Rongrong, Li, Zhenxi, Zhou, Wang, Ding, JianDong, Chu, Jianjun, Jia, Lianshun, Jia, Qi, Tan, Chengjun, Liu, Mingyao, Xiao, Jianru
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673208/
https://ncbi.nlm.nih.gov/pubmed/26090868
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