Endothelial-like malignant glioma cells in dynamic three dimensional culture identifies a role for VEGF and FGFR in a tumor-derived angiogenic response

Aims: Recent studies have observed that cells from high-grade glial tumors are capable of assuming an endothelial phenotype and genotype, a process termed ‘vasculogenic mimicry’ (VM). Here we model and manipulate VM in dynamic 3-dimensional (3D) glioma cultures. Methods: The Rotary Cell Culture Syst...

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發表在:Oncotarget
Main Authors: Smith, Stuart J., Ward, Jennifer H., Tan, Christopher, Grundy, Richard G., Rahman, Ruman
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2015
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673156/
https://ncbi.nlm.nih.gov/pubmed/26203665
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