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Jagged1 (JAG1): Structure, Expression, and Disease Associations

Jagged1 (JAG1) is one of 5 cell surface ligands that functions primarily in the highly conserved Notch signaling pathway. Notch signaling plays a critical role in cellular fate determination and is active throughout development and across many organ systems. The classic JAG1-NOTCH interaction leads...

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Bibliografiske detaljer
Udgivet i:Gene
Main Authors: Grochowski, Christopher M., Loomes, Kathleen M., Spinner, Nancy B.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673022/
https://ncbi.nlm.nih.gov/pubmed/26548814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2015.10.065
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