A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Cohorts

BACKGROUND: Systemic inflammation is a whole body reaction having an infection-positive (i.e., sepsis) or infection-negative origin. It is important to distinguish between these two etiologies early and accurately because this has significant therapeutic implications for critically ill patients. We...

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Detaylı Bibliyografya
Yayımlandı:PLoS Med
Asıl Yazarlar: McHugh, Leo, Seldon, Therese A., Brandon, Roslyn A., Kirk, James T., Rapisarda, Antony, Sutherland, Allison J., Presneill, Jeffrey J., Venter, Deon J., Lipman, Jeffrey, Thomas, Mervyn R., Klein Klouwenberg, Peter M. C., van Vught, Lonneke, Scicluna, Brendon, Bonten, Marc, Cremer, Olaf L., Schultz, Marcus J., van der Poll, Tom, Yager, Thomas D., Brandon, Richard B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672921/
https://ncbi.nlm.nih.gov/pubmed/26645559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001916
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