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Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo

The innate immune system relies to a great deal on the interaction of pattern recognition receptors with pathogen- or damage-associated molecular pattern molecules. Extracellular histones belong to the latter group and their release has been described to contribute to the induction of systemic infla...

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Publicat a:PLoS Pathog
Autors principals: Westman, Johannes, Papareddy, Praveen, Dahlgren, Madelene W., Chakrakodi, Bhavya, Norrby-Teglund, Anna, Smeds, Emanuel, Linder, Adam, Mörgelin, Matthias, Johansson-Lindbom, Bengt, Egesten, Arne, Herwald, Heiko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672907/
https://ncbi.nlm.nih.gov/pubmed/26646682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005319
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