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Rational, yet simple, design and synthesis of an antifreeze-protein inspired polymer for cellular cryopreservation

Antifreeze (glyco) proteins AF(G)Ps are potent ice recrystallization inhibitors, which is a desirable property to enhance cryopreservation of donor tissue/cells. Here we present the rational synthesis of a new, biomimetic, ice-recrystallization inhibiting polymer derived from a cheap commodity polym...

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Detalles Bibliográficos
Publicado en:Chem Commun (Camb)
Main Authors: Mitchell, Daniel E., Cameron, Neil R., Gibson, Matthew I.
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672748/
https://ncbi.nlm.nih.gov/pubmed/26176027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc04647e
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