Glucose promotes cell proliferation, glucose uptake and invasion in endometrial cancer cells via AMPK/mTOR/S6 and MAPK signaling

OBJECTIVES: Obesity and diabetes are well-known risk factors for the development of endometrial cancer. A high rate of aerobic glycolysis represents a key mechanism by which endometrial cancer cells consume glucose as its primary energy source. The up-regulated glycolytic pathway is a common therape...

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Publicado en:Gynecol Oncol
Autores principales: Han, Jianjun, Zhang, Lu, Guo, Hui, Wysham, Weiya Z., Roque, Dario R., Willson, Adam K., Sheng, Xiugui, Zhou, Chunxiao, Bae-Jump, Victoria L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672629/
https://ncbi.nlm.nih.gov/pubmed/26135947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2015.06.036
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