Identifying amyloid pathology–related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study

INTRODUCTION: The dynamic range of cerebrospinal fluid (CSF) amyloid β (Aβ(1–42)) measurement does not parallel to cognitive changes in Alzheimer's disease (AD) and cognitively normal (CN) subjects across different studies. Therefore, identifying novel proteins to characterize symptomatic AD sa...

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Publicado en:Alzheimers Dement (Amst)
Autores principales: Leung, Yuk Yee, Toledo, Jon B., Nefedov, Alexey, Polikar, Robi, Raghavan, Nandini, Xie, Sharon X., Farnum, Michael, Schultz, Tim, Baek, Young, Van Deerlin, Vivianna M., Hu, William T., Holtzman, David M., Fagan, Anne M., Perrin, Richard J., Grossman, Murray, Soares, Holly D., Kling, Mitchel A., Mailman, Matthew, Arnold, Steven E., Narayan, Vaibhav A., Lee, Virginia M-Y., Shaw, Leslie M., Baker, David, Wittenberg, Gayle M., Trojanowski, John Q., Wang, Li-San
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2015
Materias:
CSF Biomarkers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672388/
https://ncbi.nlm.nih.gov/pubmed/26693175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2015.06.008
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