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The ADAS-Cog revisited: Novel composite scales based on ADAS-Cog to improve efficiency in MCI and early AD trials

BACKGROUND: The Alzheimer’s Disease Assessment Scale-Cognitive (ADAS-Cog) has been used widely as a cognitive end point in Alzheimer’s Disease (AD) clinical trials. Efforts to treat AD pathology at earlier stages have also used ADAS-Cog, but failure in these trials can be difficult to interpret beca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Raghavan, Nandini, Samtani, Mahesh N., Farnum, Michael, Yang, Eric, Novak, Gerald, Grundman, Michael, Narayan, Vaibhav, DiBernardo, Allitia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732822/
https://ncbi.nlm.nih.gov/pubmed/23127469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2012.05.2187
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