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Hypoxia facilitates neurogenic dural plasma protein extravasation in mice: a novel animal model for migraine pathophysiology

Migraine animal models generally mimic the onset of attacks and acute treatment processes. A guinea pig model used the application of meta-chlorophenylpiperazine (mCPP) to trigger immediate dural plasma protein extravasation (PPE) mediated by 5-HT(2B) receptors. This model has predictive value for a...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Hunfeld, Anika, Segelcke, Daniel, Bäcker, Ingo, Mecheri, Badreddine, Hemmer, Kathrin, Dlugosch, Elisabeth, Andriske, Michael, Paris, Frank, Zhu, Xinran, Lübbert, Hermann
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672320/
https://ncbi.nlm.nih.gov/pubmed/26644235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17845
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