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Cell culture-derived HCV cannot infect synovial fibroblasts

Worldwide 170 million individuals are infected with hepatitis C virus (HCV), up to 45 million of whom are affected by arthropathy. It is unclear whether this is due to viral infection of synovial cells or immune-mediated mechanisms. We tested the capacity of primary synovial fibroblasts to support H...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nadeem, Abd-Elshafy D., Thomas, Pietschmann, Ulf, Müller-Ladner, Elena, Neumann, Anggakusuma, A, Mohamed, Bahgat M., Frank, Pessler, Patrick, Behrendt
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672287/
https://ncbi.nlm.nih.gov/pubmed/26643193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18043
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