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Golgi Fragmentation in ALS Motor Neurons. New Mechanisms Targeting Microtubules, Tethers, and Transport Vesicles

Pathological alterations of the Golgi apparatus, such as its fragmentation represent an early pre-clinical feature of many neurodegenerative diseases and have been widely studied in the motor neuron disease amyotrophic lateral sclerosis (ALS). Yet, the underlying molecular mechanisms have remained c...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Haase, Georg, Rabouille, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672084/
https://ncbi.nlm.nih.gov/pubmed/26696811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00448
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