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New therapeutic strategies for BRAF mutant colorectal cancers

Oncogenic BRAF mutations are found in ~10% of colorectal cancers (CRCs) and predict poor prognosis. Although BRAF inhibitors have demonstrated striking efficacy in BRAF mutant melanomas, BRAF inhibitor monotherapy is ineffective in BRAF mutant CRC. Over the past few years, studies have begun to defi...

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Bibliografiska uppgifter
I publikationen:J Gastrointest Oncol
Huvudupphovsman: Corcoran, Ryan B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: AME Publishing Company 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671849/
https://ncbi.nlm.nih.gov/pubmed/26697198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2078-6891.2015.076
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