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New therapeutic strategies for BRAF mutant colorectal cancers

Oncogenic BRAF mutations are found in ~10% of colorectal cancers (CRCs) and predict poor prognosis. Although BRAF inhibitors have demonstrated striking efficacy in BRAF mutant melanomas, BRAF inhibitor monotherapy is ineffective in BRAF mutant CRC. Over the past few years, studies have begun to defi...

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Bibliografske podrobnosti
izdano v:J Gastrointest Oncol
Glavni avtor: Corcoran, Ryan B.
Format: Artigo
Jezik:Inglês
Izdano: AME Publishing Company 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671849/
https://ncbi.nlm.nih.gov/pubmed/26697198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2078-6891.2015.076
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