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New therapeutic strategies for BRAF mutant colorectal cancers
Oncogenic BRAF mutations are found in ~10% of colorectal cancers (CRCs) and predict poor prognosis. Although BRAF inhibitors have demonstrated striking efficacy in BRAF mutant melanomas, BRAF inhibitor monotherapy is ineffective in BRAF mutant CRC. Over the past few years, studies have begun to defi...
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出版年: | J Gastrointest Oncol |
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第一著者: | |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
AME Publishing Company
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4671849/ https://ncbi.nlm.nih.gov/pubmed/26697198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2078-6891.2015.076 |
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