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New therapeutic strategies for BRAF mutant colorectal cancers

Oncogenic BRAF mutations are found in ~10% of colorectal cancers (CRCs) and predict poor prognosis. Although BRAF inhibitors have demonstrated striking efficacy in BRAF mutant melanomas, BRAF inhibitor monotherapy is ineffective in BRAF mutant CRC. Over the past few years, studies have begun to defi...

詳細記述

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書誌詳細
出版年:J Gastrointest Oncol
第一著者: Corcoran, Ryan B.
フォーマット: Artigo
言語:Inglês
出版事項: AME Publishing Company 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671849/
https://ncbi.nlm.nih.gov/pubmed/26697198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2078-6891.2015.076
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