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New therapeutic strategies for BRAF mutant colorectal cancers

Oncogenic BRAF mutations are found in ~10% of colorectal cancers (CRCs) and predict poor prognosis. Although BRAF inhibitors have demonstrated striking efficacy in BRAF mutant melanomas, BRAF inhibitor monotherapy is ineffective in BRAF mutant CRC. Over the past few years, studies have begun to defi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Gastrointest Oncol
Päätekijä: Corcoran, Ryan B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: AME Publishing Company 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671849/
https://ncbi.nlm.nih.gov/pubmed/26697198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2078-6891.2015.076
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