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New therapeutic strategies for BRAF mutant colorectal cancers

Oncogenic BRAF mutations are found in ~10% of colorectal cancers (CRCs) and predict poor prognosis. Although BRAF inhibitors have demonstrated striking efficacy in BRAF mutant melanomas, BRAF inhibitor monotherapy is ineffective in BRAF mutant CRC. Over the past few years, studies have begun to defi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Gastrointest Oncol
Egile nagusia: Corcoran, Ryan B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: AME Publishing Company 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671849/
https://ncbi.nlm.nih.gov/pubmed/26697198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2078-6891.2015.076
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