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BRAF mutant colorectal cancer as a distinct subset of colorectal cancer: clinical characteristics, clinical behavior, and response to targeted therapies

Despite new and more effective cytotoxic chemotherapy, limitations to conventional agents have been reached in a subset of patients with advanced colorectal cancer (CRC). The identification of novel prognostic and predictive biomarkers to guide individualized treatment plans is critical to overcomin...

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Pubblicato in:J Gastrointest Oncol
Autori principali: Clarke, Callisia N., Kopetz, E. Scott
Natura: Artigo
Lingua:Inglês
Pubblicazione: AME Publishing Company 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671844/
https://ncbi.nlm.nih.gov/pubmed/26697199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2078-6891.2015.077
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