Inhibition of FOXO1 by small interfering RNA enhances proliferation and inhibits apoptosis of papillary thyroid carcinoma cells via Akt/FOXO1/Bim pathway

Forkhead box protein O1 (FOXO1) is a multifunctional transcription factor of the forkhead family. It may function as a tumor suppressor through its ability to regulate cellular events, including cell proliferation, apoptosis, and cell cycle control. As reported, FOXO1 is downregulated in papillary t...

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Bibliografiske detaljer
Udgivet i:Onco Targets Ther
Main Authors: Song, Hong-ming, Song, Jia-lu, Li, Deng-feng, Hua, Kai-yao, Zhao, Bing-kun, Fang, Lin
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671809/
https://ncbi.nlm.nih.gov/pubmed/26664140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S95395
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