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Profile of secukinumab in the treatment of psoriasis: current perspectives

Secukinumab (Cosentyx™) is a human monoclonal IgG1k antibody that has been developed to target and block the actions of IL-17A. It is known that this cytokine is elevated in lesions of psoriasis. Interleukins in the Th17 pathway play a pivotal role in the pathogenesis of psoriasis and have thus beco...

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Podrobná bibliografie
Vydáno v:Ther Clin Risk Manag
Hlavní autoři: Roman, Michael, Madkan, Vandana K, Chiu, Melvin W
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671779/
https://ncbi.nlm.nih.gov/pubmed/26664127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S79053
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