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Factors Affecting the Timing of Signal Detection of Adverse Drug Reactions

We investigated factors affecting the timing of signal detection by comparing variations in reporting time of known and unknown ADRs after initial drug release in the USA. Data on adverse event reactions (AERs) submitted to U.S. FDA was used. Six ADRs associated with 6 drugs (rosuvastatin, aripipraz...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hashiguchi, Masayuki, Imai, Shungo, Uehara, Keiko, Maruyama, Junya, Shimizu, Mikiko, Mochizuki, Mayumi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671724/
https://ncbi.nlm.nih.gov/pubmed/26641634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144263
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