Gene Delivery by Subconjunctival Injection of Adenovirus in Rats: A Study of Local Distribution, Transgene Duration and Safety

Subconjunctival injection is a minimally invasive route for gene delivery to ocular tissues, but has traditionally been limited to use in the cornea. The accurate ocular distribution of virus has not, however, been previously investigated. Adenovirus is an attractive gene vector as it can deliver la...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Liu, Guei-Sheung, Wang, Jiang-Hui, Lee, Jia Hui, Tsai, Pei-Jhen, Tsai, Han-En, Sheu, Shwu-Jiuan, Lin, Hsiu-Chen, Dusting, Gregory J., Tai, Ming-Hong, Bee, Youn-Shen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671571/
https://ncbi.nlm.nih.gov/pubmed/26642208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143956
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