Deletion of ripA Alleviates Suppression of the Inflammasome and MAPK by Francisella tularensis

Francisella tularensis is a facultative intracellular pathogen and potential biothreat agent. Evasion of the immune response contributes to the extraordinary virulence of this organism although the mechanism is unclear. Whereas wild-type strains induced low levels of cytokines, an F. tularensis ripA...

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Veröffentlicht in:J Immunol
Hauptverfasser: Huang, Max Tze-Han, Mortensen, Brittany L., Taxman, Debra J., Craven, Robin R., Taft-Benz, Sharon, Kijek, Todd M., Fuller, James R., Davis, Beckley K., Allen, Irving Coy, Brickey, Willie June, Gris, Denis, Wen, Haitao, Kawula, Thomas H., Ting, Jenny Pan-Yun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671501/
https://ncbi.nlm.nih.gov/pubmed/20921527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002154
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