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Functional roles of alternative splicing factors in human disease

Alternative splicing (AS) is an important mechanism used to generate greater transcriptomic and proteomic diversity from a finite genome. Nearly all human gene transcripts are alternatively spliced and can produce protein isoforms with divergent and even antagonistic properties that impact cell func...

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Detalhes bibliográficos
Publicado no:Wiley Interdiscip Rev RNA
Main Authors: Cieply, Benjamin, Carstens, Russ P
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671264/
https://ncbi.nlm.nih.gov/pubmed/25630614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1276
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