A synthetic modular approach for modeling the role of the 3D microenvironment in tumor progression

Here, we demonstrate the flexibility of peptide-functionalized poly(ethylene glycol) (PEG) hydrogels for modeling tumor progression. The PEG hydrogels were formed using thiol-ene chemistry to incorporate a matrix metalloproteinase-degradable peptide crosslinker (KKCGGPQG↓IWGQGCKK) permissive to prot...

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Publicat a:Sci Rep
Autors principals: Singh, S. P., Schwartz, M. P., Tokuda, E. Y., Luo, Y., Rogers, R. E., Fujita, M., Ahn, N. G., Anseth, K. S.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671067/
https://ncbi.nlm.nih.gov/pubmed/26638791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17814
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