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GLUT3 and PKM2 regulate OCT4 expression and support the hypoxic culture of human embryonic stem cells
Human embryonic stem cells (hESCs) have the capacity to differentiate into all cell types and thus have great potential for regenerative medicine. hESCs cultured at low oxygen tensions are more pluripotent and display an increased glycolytic rate but how this is regulated is unknown. This study ther...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4671001/ https://ncbi.nlm.nih.gov/pubmed/26639784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17500 |
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