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Stress and Cocaine Trigger Divergent and Cell Type-Specific Regulation of Synaptic Transmission at Single Spines in Nucleus Accumbens

BACKGROUND: Repeated exposure to cocaine or social stress leads to lasting structural and functional synaptic alterations in medium spiny neurons (MSNs) of nucleus accumbens (NAc). While cocaine- and stress-induced structural changes in dendritic spines have been well-documented, few studies have in...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Khibnik, Lena A., Beaumont, Michael, Doyle, Marie, Heshmati, Mitra, Slesinger, Paul A., Nestler, Eric J., Russo, Scott J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670821/
https://ncbi.nlm.nih.gov/pubmed/26164802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.05.022
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