A Genomic Study of DNA Alteration Events Caused by Ionizing Radiation in Human Embryonic Stem Cells via Next-Generation Sequencing

Ionizing radiation (IR) is a known mutagen that is widely employed for medical diagnostic and therapeutic purposes. To study the extent of genetic variations in DNA caused by IR, we used IR-sensitive human embryonic stem cells (hESCs). Four hESC cell lines, H1, H7, H9, and H14, were subjected to IR...

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Bibliographic Details
Published in:Stem Cells Int
Main Authors: Nguyen, Van, Panyutin, Irina V., Panyutin, Igor G., Neumann, Ronald D.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670683/
https://ncbi.nlm.nih.gov/pubmed/26709353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1346521
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