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Metallothionein-3 modulates the amyloid β endocytosis of astrocytes through its effects on actin polymerization
BACKGROUND: Astrocytes may play important roles in the pathogenesis of Alzheimer’s disease (AD) by clearing extracellular amyloid beta (Aβ) through endocytosis and degradation. We recently showed that metallothionein 3 (Mt3), a zinc-binding metallothionein that is enriched in the central nervous sys...
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| 出版年: | Mol Brain |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4670512/ https://ncbi.nlm.nih.gov/pubmed/26637294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0173-3 |
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