The defining pathology of the new clinical and histopathologic entity ACTA2-related cerebrovascular disease

INTRODUCTION: Smooth muscle cell contraction is an essential function of arteries and relies on the integrity of the actin-myosin apparatus. The tissue-specific α2-smooth muscle actin, encoded by ACTA2, is predominantly expressed in vascular smooth muscle cells. ACTA2 mutations predispose to develop...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Georgescu, Maria-Magdalena, Pinho, Marco da Cunha, Richardson, Timothy E., Torrealba, Jose, Buja, L. Maximilian, Milewicz, Dianna M., Raisanen, Jack M., Burns, Dennis K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670506/
https://ncbi.nlm.nih.gov/pubmed/26637293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0262-7
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