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Synthesis of 2,3,5,6-tetrafluoro-pyridine derivatives from reaction of pentafluoropyridine with malononitrile, piperazine and tetrazole-5-thiol

Some pentafluoropyridine derivatives have been synthesized by the reaction of pentafluoropyridine with appropriate C, S and N-nucleophile such as malononitrile, 1-methyl-tetrazole-5-thiol and piperazine. These reactions provided 4-substituted 2,3,5,6-tetrafluoropyridine derivatives in good yields. A...

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Detalhes bibliográficos
Publicado no:Springerplus
Main Authors: Beyki, Khalil, Haydari, Reza, Maghsoodlou, Malek Taher
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670442/
https://ncbi.nlm.nih.gov/pubmed/26674807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-015-1495-4
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