Evaluation of the Genetic Basis of Familial Aggregation of Pacemaker Implantation by a Large Next Generation Sequencing Panel

BACKGROUND: The etiology of conduction disturbances necessitating permanent pacemaker (PPM) implantation is often unknown, although familial aggregation of PPM (faPPM) suggests a possible genetic basis. We developed a pan-cardiovascular next generation sequencing (NGS) panel to genetically character...

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Vydáno v:PLoS One
Hlavní autoři: Celestino-Soper, Patrícia B. S., Doytchinova, Anisiia, Steiner, Hillel A., Uradu, Andrea, Lynnes, Ty C., Groh, William J., Miller, John M., Lin, Hai, Gao, Hongyu, Wang, Zhiping, Liu, Yunlong, Chen, Peng-Sheng, Vatta, Matteo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670209/
https://ncbi.nlm.nih.gov/pubmed/26636822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143588
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