Llwytho...
A Computational View On the Significance of E-Ring in Binding of (+)-Arisugacin A to Acetylcholinesterase
A computational docking study of a series of de novo structural analogs of the highly potent, non-nitrogen containing, acetylcholinesterase inhibitor (+)-arisugacin A is presented. In direct comparison to the recently reported X-ray single-crystal structure of (+)-territrem B bound hAChE, the modeli...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Bioorg Med Chem Lett |
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Prif Awduron: | , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
2015
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4670034/ https://ncbi.nlm.nih.gov/pubmed/26159481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.06.047 |
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