Llwytho...

A Computational View On the Significance of E-Ring in Binding of (+)-Arisugacin A to Acetylcholinesterase

A computational docking study of a series of de novo structural analogs of the highly potent, non-nitrogen containing, acetylcholinesterase inhibitor (+)-arisugacin A is presented. In direct comparison to the recently reported X-ray single-crystal structure of (+)-territrem B bound hAChE, the modeli...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioorg Med Chem Lett
Prif Awduron: Al-Rashid, Ziyad F., Hsung, Richard P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670034/
https://ncbi.nlm.nih.gov/pubmed/26159481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.06.047
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