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Ultrasound-guided RNA interference targeting HIF-1 alpha improves the effects of transarterial chemoembolization in rat liver tumors

AIM: To investigate whether ultrasound-guided RNA interference (RNAi) targeting hypoxia-inducible factor-1alpha (HIF-1α) can enhance the efficacy of transarterial chemoembolization (TACE) in treating hepatocellular carcinoma. MATERIALS AND METHODS: Rats with orthotopic hepatocellular carcinoma were...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Chen, Cheng-Shi, Zhao, Qing, Qian, Sheng, Li, Hai-Liang, Guo, Chen-Yang, Zhang, Wei, Yan, Zhi-Ping, Liu, Rong, Wang, Jian-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669929/
https://ncbi.nlm.nih.gov/pubmed/26664137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S94800
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