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The XRCC1 Arg194Trp polymorphism is significantly associated with lung adenocarcinoma: a case-control study in an Eastern European Caucasian group

DNA repair plays an important role in maintaining the integrity of the genome by repairing DNA damage induced by carcinogens. Certain genetic polymorphisms that occur in DNA-repair genes may affect the ability to repair DNA defects, and may represent a risk factor in carcinogenesis. The gene XRCC1 i...

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Vydáno v:Onco Targets Ther
Hlavní autoři: Cătană, Andreea, Pop, Monica, Hincu, Bianca Domokos, Pop, Ioan V, Petrişor, Felicia M, Porojan, Mihai D, Popp, Radu A
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669918/
https://ncbi.nlm.nih.gov/pubmed/26664136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S92361
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