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Effects of Trichostatin A on drug uptake transporters in primary rat hepatocyte cultures

The present study was set up to investigate the effects of Trichostatin A (TSA), a prototypical epigenetic modifier, on the expression and activity of hepatic drug uptake transporters in primary cultured rat hepatocytes. To this end, the expression of the sinusoidal transporters sodium-dependent tau...

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Detalhes bibliográficos
Publicado no:EXCLI J
Main Authors: Ramboer, Eva, Rogiers, Vera, Vanhaecke, Tamara, Vinken, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado em: Leibniz Research Centre for Working Environment and Human Factors 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669911/
https://ncbi.nlm.nih.gov/pubmed/26648816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2015-220
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