LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.

Androgens, in particular dihydrotestosterone (DHT), play a key role in differentiation, growth, and maintenance of the mammalian prostate. Production of DHT from testosterone is catalyzed by two distinct membrane-bound steroid 5 alpha-reductase [5 alpha-reductase; 3-oxo-5 alpha-steroid delta 4-dehyd...

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Autors principals: Hirsch, K S, Jones, C D, Audia, J E, Andersson, S, McQuaid, L, Stamm, N B, Neubauer, B L, Pennington, P, Toomey, R E, Russell, D W
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC46699/
https://ncbi.nlm.nih.gov/pubmed/8389478
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