Arrestin 1 and Cone Arrestin 4 Have Unique Roles in Visual Function in an All-Cone Mouse Retina

PURPOSE: Previous studies discovered cone phototransduction shutoff occurs normally for Arr1(−/−) and Arr4(−/−); however, it is defective when both visual arrestins are simultaneously not expressed (Arr1(−/−)Arr4(−/−)). We investigated the roles of visual arrestins in an all-cone retina (Nrl(−/−)) s...

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Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Deming, Janise D., Pak, Joseph S., Shin, Jung-a, Brown, Bruce M., Kim, Moon K., Aung, Moe H., Lee, Eun-Jin, Pardue, Machelle T., Craft, Cheryl Mae
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2015
Fag:
Biochemistry and Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669854/
https://ncbi.nlm.nih.gov/pubmed/26624493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17832
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