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Reactive oxygen species-mediated therapeutic response and resistance in glioblastoma

Glioblastoma (GBM) resistance to therapy is the most common cause of tumor recurrence, which is ultimately fatal in 90% of the patients 5 years after initial diagnosis. A sub-population of tumor cells with stem-like properties, glioma stem cells (GSCs), is specifically endowed to resist or adapt to...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Singer, E, Judkins, J, Salomonis, N, Matlaf, L, Soteropoulos, P, McAllister, S, Soroceanu, L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669764/
https://ncbi.nlm.nih.gov/pubmed/25590811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.566
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