Identification of acetyltransferase genes (HAT1 and KAT8) regulating HBV replication by RNAi screening

BACKGROUND: The initiation of hepatitis B virus (HBV) replication involves the formation of covalently closed circular DNA (cccDNA) and its transcription into pregenomic RNA (pgRNA) in hepatocyte nuclei. The regulatory mechanism of HBV replication by acetyltransferase is thus far not well understood...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Wang, Hui, Liu, KeHui, Fang, Bernard A. M., Wu, HaiQing, Li, FengDi, Xiang, XiaoGang, Tang, WeiLiang, Zhao, GangDe, Lin, LanYi, Bao, Shisan, Xie, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669656/
https://ncbi.nlm.nih.gov/pubmed/26640654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-015-0059-1
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