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SIGIRR participates in negative regulation of LPS response and tolerance in human bladder epithelial cells

BACKGROUND: The innate immune response of urinary tract is critically important in the defense to microbial attack. Toll-like receptor 4 (TLR4) controls initial mucosal response to uropathogenic Escherichia coli (UPEC). However, excessive and dysfunctional TLR signaling may result in severe inflamma...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Li, Dan, Zhang, Xin, Chen, Baiyi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669620/
https://ncbi.nlm.nih.gov/pubmed/26634342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-015-0137-5
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