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Defining the Schistosoma haematobium kinome enables the prediction of essential kinases as anti-schistosome drug targets

The blood fluke Schistosoma haematobium causes urogenital schistosomiasis, a neglected tropical disease (NTD) that affects more than 110 million people. Treating this disease by targeted or mass administration with a single chemical, praziquantel, carries the risk that drug resistance will develop i...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Stroehlein, Andreas J., Young, Neil D., Jex, Aaron R., Sternberg, Paul W., Tan, Patrick, Boag, Peter R., Hofmann, Andreas, Gasser, Robin B.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669435/
https://ncbi.nlm.nih.gov/pubmed/26635209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17759
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