A Proteomics Approach to Investigate miR-153-3p and miR-205-5p Targets in Neuroblastoma Cells

MicroRNAs are key regulators associated with numerous diseases. In HEK293 cells, miR-153-3p and miR-205-5p down-regulate alpha-synuclein (SNCA) and Leucine-rich repeat kinase 2 (LRRK2), two key proteins involved in Parkinson’s disease (PD). We have used two-dimensional gel electrophoresis (2D-PAGE)...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Patil, Ketan S., Basak, Indranil, Pal, Ramavati, Ho, Hsin-Pin, Alves, Guido, Chang, Emmanuel J., Larsen, Jan Petter, Møller, Simon Geir
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669106/
https://ncbi.nlm.nih.gov/pubmed/26633009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143969
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