Phase I Clinical Trials in Acute Myeloid Leukemia: 23-Year Experience From Cancer Therapy Evaluation Program of the National Cancer Institute

BACKGROUND: Therapy for acute myeloid leukemia (AML) has largely remained unchanged, and outcomes are unsatisfactory. We sought to analyze outcomes of AML patients enrolled in phase I studies to determine whether overall response rates (ORR) and mortality rates have changed over time. METHODS: A ret...

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Vydáno v:J Natl Cancer Inst
Hlavní autoři: Zeidner, Joshua F., Karp, Judith E., Blackford, Amanda L., Foster, Matthew C., Dees, E. Claire, Smith, Gary, Ivy, S. Percy, Harris, Pamela
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668761/
https://ncbi.nlm.nih.gov/pubmed/26553781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv335
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