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Preclinical detection of infectivity and disease-specific PrP in blood throughout the incubation period of prion disease
Variant Creutzfeldt-Jakob disease (vCJD) is a fatal neurodegenerative disorder characterised by accumulation of pathological isoforms of the prion protein, PrP. Although cases of clinical vCJD are rare, there is evidence there may be tens of thousands of infectious carriers in the United Kingdom alo...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4668555/ https://ncbi.nlm.nih.gov/pubmed/26631638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17742 |
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